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Partially Occlusive Thrombus
Lipid Necrotic Core
Thinned Ruptured shoulder intima
Thickened Intima Media
Heart attack usually occur in individuals with long-standing coronary artery disease. However, it can occur in individuals with early coronary artery disease as well as in the 20s and 30s with disastrous results.
In men most heart attacks are caused by a ruptured vascular pimple superimposed on chronic coronary artery disease to which the body reacts by forming a clot and closes off the blood flow to the heart muscle.
In women many heart attacks occur from an erosion of the lining of the artery over a cholesterol plaque to which the body responds by forming a clot
If the coronary artery is feeding a large area of muscle, a large heart attack occurs known as ST segment elevation myocardial infarction or STEMI. Naturally less damage to the heart would be preferable. However, even a small damage in a critical area of the heart can lead to dire consequences(e,g, sudden cardiac death or delayed serious ventricular arrhythmias and congestive heart failure secondary to dyssynchrony of the heart or involvement of the mitral valve apparatus.
If the clot is partially occlusive or if the clot is partially dissolved by the bodies protective mechanisms, a condition called acute coronary syndrome occurs(unstable angina). This can lead to only partial destruction of the heart wall thickness, the so-called non-ST segment elevation myocardial infarction, NSTEMI or sub endocardial myocardial infarction
The ideal situation is to never have the first heart attack by preventing the vulnerable atherosclerotic from developing.. That is the mission of CVRRUSA. Contact Us
Eroded Lining Common in Women heart attacks
Non Occlusive Blood Clot, ACS, Inner heart wall damage
Occluded Artery, Eroded Lining with clot, Common full wall thickness damage in women
Ruptured vascular pimple, ACS or inner muscle wall thickness damage, usually in men
The vulnerable plaque is prone to rupture or erode, producing clot of varying sizes. A partially occlusive clot causes unstable angina (chest pain usually at rest), acute coronary syndrome (ACS), or subendocardial myocardial infarction (a partial wall thickness death of the heart muscle wall).
A totally occlusive clot usually causes a transmural heart attack (through and through death of the heart muscle wall).
Usually, if there is one of these symptomatic clots present, there are varying amounts of additional non-symptomatic clots. These non-symptomatic clots are happening all the time, even in the asymptomatic individuals as long as vulnerable plaques are present. The bullets ( clots on the vulnerable plaque) to the gun are loaded all the time when these" vascular pimples" are present. It is similar to to a game of Russian Roulette.
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